The decision announced Tuesday would allow the Davis-Besse plant near Toledo to stay in operation until 2037.
The Nuclear Regulatory Commission has spent the last couple of years reviewing the plant's safety and operations records and its environmental impact.
The move was not a surprise after regulators said two years ago that there were no safety issues standing in the way of renewing the operating license
The plant that sits along Lake Erie is run by the FirstEnergy Nuclear Operating Co.
Several anti-nuclear groups opposed the license renewal after cracks were found in the plant's concrete shell four years ago.
Plant operators said the cracks trace back to a 1978 blizzard and didn't pose a danger.